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Reference type: Journal
Authors: Schirhagl R, Lieberzeit PA, Blaas D, Dickert FL
Article Title: Chemosensors for Viruses Based on Artificial Immunoglobulin Copies.
Publication date: 2010
Journal: Advanced Materials
Volume: 22
Issue: (18)
Page numbers: 2078-2081.
DOI: 10.1002/adma.200903517

Abstract: 'Plastic replicas' of natural antibodies are accessible by molecular imprinting procedures. The first step involves the synthesis of molecularly imprinted polymer (MIP) particles templated with human immunoglobulin. They then can be utilized as templates for a stamp-based surface imprinting procedure that results in polymer surface structures exactly mimicking the initial globulin. Compared to their natural counterparts, these artificial antibodies show improved selectivity and sensitivity on quartz crystal microbalance sensors
Template and target information: protein, human immunoglobulin, antibody replicas
Author keywords: artificial receptors, Immunoglobulins, molecular imprinting, quartz crystal microbalance, self-assembly, sensors


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