Authors: Kugimiya A
, Mukawa T
, Takeuchi T
Synthesis of 5-fluorouracil-imprinted polymers with multiple hydrogen bonding interactions.
Publication date: 2001
Abstract: The antitumor active compound 5-fluorouracil (5-FU) was used as a target molecule and 5-FU-imprinted polymers were synthesized using 2,6-bis(acrylamido)pyridine and/or 2- (trifluoromethyl)acrylic acid as functional monomers. The 5-FU- imprinted polymers showed a higher affinity for 5-FU than that for 5-FU derivatives. By using both functional monomers simultaneously, the affinity and separation for 5-FU were improved
Template and target information: 5-fluorouracil, 5-FU
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