Authors: Liu JQ
, Luo GM
, Gao SJ
, Zhang K
, Chen XF
, Shen JC
Generation of a glutathione peroxidase-like mimic using bioimprinting and chemical mutation.
Publication date: 1999
Journal: Chemical Communications
Abstract: Molecular imprinting of albumin with N,S-bis(2,4- dinitrophenyl)glutathione (GSH-2DNP), a glutathione (GSH) derivative, leads to an imprinted protein with GSH binding sites; chemical mutation of the protein results in formation of an artificial enzyme with high glutathione peroxidase (GPX) activity
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