Authors: Chen LN
, Du SH
, Ma KF
, Cai Z
Application of Molecular Imprinting Technology for Separation of Puerarin and Effect of Solvent on Recognition of Molecularly Imprinted Polymer.
Publication date: 2008
Journal: Chemistry and Industry of Forest Products
Alternative URL: http://en.cnki.com.cn/Article_en/CJFDTotal-LCHX200803005.htm
Abstract: A rational design approach was taken to the planning and synthesis of a molecularly imprinted polymer(MIP)capable of extracting puerarin from pueraria extract.The polymer was evaluated by static adsorption experiment.A molecular modeling approach was used to elucidate template-monomer interaction.Data from spectral analysis were used to prove the prediction made by molecular modeling.The MIPs have high selectivity to puerarin,the recovery rate of puerarin at 78.0 %,and purity at 86.5 % were attained.The successful preparation of molecular-imprinted polymers for solid-phase extraction for puerarin provides an innovative opportunity for the separation of traditional Chinese medicine.
Template and target information: puerarin
Author keywords: Puerarin, molecular imprinting, SPE, molecular modeling
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