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Reference type: Journal
Authors: Kumar D, Prasad BB
Article Title: Multiwalled carbon nanotubes embedded molecularly imprinted polymer-modified screen printed carbon electrode for the quantitative analysis of C-reactive protein.
Publication date: 2012
Journal: Sensors and Actuators B: Chemical
Volume: 171-172
Page numbers: 1141-1150.
DOI: 10.1016/j.snb.2012.06.053
Alternative URL: http://www.sciencedirect.com/science/article/pii/S0925400512006284

Abstract: In this work, we have applied the principle of biomimiking by incorporating 2-acryl amidoethyldihydrogen phosphate monomer which acts as if phosphotidyl choline natural binder in the synthesis of a novel C-reactive protein imprinted polymer. For C-reactive protein determination, an imprinted polymer modified screen printed carbon electrode fabricated adapting ''grafting-to'' modification was used. The modified surface was characterized by atomic force microscopy and scanning electron microscopy analyses. The limit of detection was found to be 0.04 μg mL-1 (S/N = 3) in aqueous environment. To validate the methodology and efficacy of proposed sensor, detection of C-reactive protein was also examined in human blood serum
Template and target information: protein, C-reactive protein
Author keywords: C-reactive protein, Screen-printed carbon electrode, molecularly imprinted polymer, surface imprinting, Potassium ferrocyanide probe, differential pulse voltammetry


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