MIPs logo MIPdatabase      Use this space
Custom Search
Reference type: Journal
Authors: Madrakian T, Afkhami A, Mahmood-Kashani H, Ahmadi M
Article Title: Superparamagnetic surface molecularly imprinted nanoparticles for sensitive solid-phase extraction of tramadol from urine samples.
Publication date: 2013
Journal: Talanta
Volume: 105
Page numbers: 255-261.
DOI: 10.1016/j.talanta.2012.12.039
Alternative URL: http://www.sciencedirect.com/science/article/pii/S0039914012010739

Abstract: A rapid, selective, sensitive and accurate method based on superparamagnetic molecularly imprinted polymer nanoparticles (MMIPNPs) was developed for the determination of tramadol (TRA) in human urine samples. The MMIPNPs were prepared by coating SiO2Gă˘Fe3O4 nanoparticles with polyaminoimide homopolymer and TRA as the template. The prepared MMIPNPs adsorbent was characterized by TEM, FT-IR, XRD and magnetometry. TEM images show that the Fe3O4 nanoparticles are well-enwrapped by the SiO2 shell and further by an MIP layer. The prepared magnetic adsorbent is well dispersed in water and can be easily separated magnetically from the medium after loading with the adsorbate. Various parameters affecting the extraction efficiency of the MMIPNPs have been evaluated. The extracted TRA could be easily desorbed with a mixture of methanol and acetic acid and determined spectrophotometrically at 272 nm. A linear dynamic range was established from 3.0 to 200.0 ng mL-1 of TAR and the limit of detection was found to be 1.5 ng mL-1. The proposed method was successfully applied for the determination of TRA in human urine samples
Template and target information: tramadol, TRA
Author keywords: molecularly imprinted polymer, magnetic nanoparticles, Tramadol, Solid-phase extraction

  I love MIPs apron  multi MIPs logo mug  British periodic table patriotic tote bag

Molecules Special Issue call      Appeal for information


Join the Society for Molecular Imprinting
Logo of the Society for Molecular Imprinting

New items RSS feed
new items RSS feed  View latest updates

Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.

Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
Other products you may like:
view listings for MIP books on eBay:

Mickey Mouse 90th Anniversary banner