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Reference type: Journal
Authors: Liu LJ, Xu ZL, Zhang Y
Article Title: Preparation and chiral resolution performance of S-ibuprofen molecularly imprinted membranes.
Publication date: 2012
Journal: Polymer Materials Science and Engineering
Volume: 28
Issue: (12)
Page numbers: 159-163.

Abstract: S-ibuprofen molecularly imprinted membrane was prepared using PVDF hollow fiber membrane as the support. The selective binding properties and chiral resolution performance of the membranes were investigated. The results show that the S-ibuprofen molecularly imprinted membrane has the high binding capacity for S-ibuprofen, the binding amount for S-ibuprofen is up to 22.8 μmol/g. Permeation experiments of S-ibuprofen and R-ibuprofen across the membrane imprinted with S-ibuprofen show that the membrane is enantioselective, diffusion of the template enantiomer faster than that of its optical antipode. The separation factor is up to 1.17. The permeation mechanism coincides with "facilitated transport" or "facilitated diffusion" model. The SEM results also indicate that a thin imprinted membrane is coated on the surface of the PVDF hollow fiber membrane
Template and target information: S-ibuprofen
Author keywords: chiral resolution, ibuprofen, molecularly imprinted membrane

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