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Reference type: Journal
Authors: Yang C, Luan XJ, Zhao MF, Liu GF, Wang JA, Qu QS, Hu XY
Article Title: Pending templates imprinted polymers - hypothesis, synthesis, adsorption, and chromatographic properties.
Publication date: 2013
Journal: Electrophoresis
Volume: 34
Issue: (9-10)
Page numbers: 1383-1389.
DOI: 10.1002/elps.201200589

Abstract: This is the first time when protein-imprinted polymers are prepared with ''pending templates.'' The polymers were synthesized in the presence of a real sample (chicken egg white), rather than any known commercial proteins. Compared with a simultaneously synthesized nonimprinted control polymer, the polymers show higher adsorption capacity for abundant components (as ''pending templates'' ) in the original sample. Chromatography experiments indicated that the columns made of the imprinted polymers could retain abundant species (imprinted) and separate them from those not imprinted. Thus, the sample could be split into dimidiate subfractions with reduced complexities. ''Pending template imprinting'' suggests a new way to investigate molecular imprinting, especially to dissect, simplify, and analyze complicated samples through a series of polymers just imprinted by the samples per se
Template and target information: protein, pending templates, chicken egg white
Author keywords: molecular-imprinted polymer, Pending templates, protein, Sample fractionation

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