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Reference type: Journal
Authors: Tadi KK, Divakarla PS, Motghare RV
Article Title: Synthesis and Characterization of Pindolol Imprinted Polymer.
Publication date: 2013
Journal: Transactions of the Indian Institute of Metals
Volume: 66
Issue: (4)
Page numbers: 349-352.
DOI: 10.1007/s12666-013-0273-7
Alternative URL: https://www.researchgate.net/publication/257794547_Synthesis_and_Characterization_of_Pindolol_Imprinted_Polymer

Abstract: Molecularly imprinted polymers (MIPs) are capable of recognizing a particular molecule in presence of others due to the selective cavities on it and thus are known as plastic antibodies. Pindolol (PDL) is a synthetic beta-adrenergic receptor blocking agent and widely used for the treatment of hypertension, cardiac arrhythmia and angina pectoris. Using a combinatorial method PDL imprinted polymers were prepared with three functional monomers viz., itaconic acid, 4-vinylpyridine and methacrylic acid by thermal initiated bulk polymerization technique using ethylene glycol dimethacrylate, 2, 2'-azobisisobutyronitrile and acetonitrile as crosslinker, initiator and solvent respectively. Among the three, PDL-itaconic acid MIP shows the best binding capacity. The PDL imprinted polymer was characterized by FTIR spectra and morphology was studied by SEM images. The binding parameters of MIP and non-imprinted polymer (NIP) were compared by the Freundlich and Langmuir adsorption isotherms
Template and target information: pindolol, PDL
Author keywords: Pindolol imprinted polymer, FTIR Spectra, SEM images, Adsorption experiments


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