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Reference type: Journal
Authors: Wang F, Zhu LH, Zhang JD
Article Title: Electrochemical sensor for levofloxacin based on molecularly imprinted polypyrrole-graphene-gold nanoparticles modified electrode.
Publication date: 2014
Journal: Sensors and Actuators B: Chemical
Volume: 192
Page numbers: 642-647.
DOI: 10.1016/j.snb.2013.11.037
Alternative URL: http://www.sciencedirect.com/science/article/pii/S0925400513013798

Abstract: A novel strategy was developed for the construction of a highly sensitive levofloxacin (LEV) sensor based on molecularly imprinted polymer (MIP) incorporation with grapheneGă˘Au nanoparticles (G-AuNPs). In this sensor, G-AuNPs dramatically promoted the electrooxidation of LEV on electrode while molecularly imprinted polypyrrole of LEV served as the recognition element. The electropolymerization conditions, method of template removal, and effects of supporting electrolyte and incubation time were investigated. Under optimized conditions, the oxidation peak current increased linearly with the concentration of LEV in the range from 1.0 to 100 μmol L-1 with a detection limit (S/N = 3) of 0.53 μmol L-1. The MIP/G-AuNPs-based sensor was useful for the determination of LEV with high sensitivity, excellent selectivity and good reproducibility
Template and target information: levofloxacin, LEV
Author keywords: molecularly imprinted polymer, polypyrrole, Graphene, gold nanoparticles, Levofloxacin

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