Reference type: Journal
Authors: Yang YK, Fang GZ, Wang XM, Pan MF, Qian HL, Liu HL, Wang S
Article Title: Sensitive and selective electrochemical determination of quinoxaline-2-carboxylic acid based on bilayer of novel poly(pyrrole) functional composite using one-step electro-polymerization and molecularly imprinted poly(o-phenylenediamine).
Publication date: 2014
Journal: Analytica Chimica Acta
Volume: 806
Page numbers: 136-143.
DOI: 10.1016/j.aca.2013.11.023
Alternative URL: http://www.sciencedirect.com/science/article/pii/S0003267013014426

Abstract: A facile and efficient molecularly imprinted polymer (MIP) recognition element of electrochemical sensor was fabricated by directly electro-polymerizing monomer o-phenylenediamine (oPD) in the presence of template quinoxaline-2-carboxylic acid (QCA), based on one-step controllable electrochemical modification of poly(pyrrole)-graphene oxide-binuclear phthalocyanine cobalt (II) sulphonate (PPY-GO-BiCoPc) functional composite on glassy carbon electrode (GCE). The MIP film coated on PPY-GO-BiCoPc functional composite decorated GCE (MIP/PPY-GO-BiCoPc/GCE) was presented for the first time. The synergistic effect and electro-catalytic activity toward QCA redox of PPY-GO-BiCoPc functional composite were discussed using various contrast tests. Also, the effect of experimental variables on the current response such as, electro-polymerization cycles, template/monomer ratio, elution condition for template removal, pH of the supporting electrolyte and accumulation time, were investigated in detail. Under the optimized conditions, the proposed MIP sensor possessed a fast rebinding dynamics and an excellent recognition capacity to QCA, while the anodic current response of square wave voltammetry (SWV) was well-proportional to the concentration of QCA in the range of 1.0 x 10-8 - 1.0 x 10-4 and 1.0 x 10-4 - 5.0 x 10-4 mol L-1 with a low detection limit of 2.1 nmol L-1. The established sensor was applied successfully to determine QCA in commercial pork and chicken muscle samples with acceptable recoveries (91.6-98.2%) and satisfactory precision (1.9-3.5% of SD), demonstrating a promising feature for applying the MIP sensor to the measurement of QCA in real samples
Template and target information: quinoxaline-2-carboxylic acid, QCA
Author keywords: Electrochemical sensor, Molecularly imprinted poly(o-phenylenediamine), Poly(pyrrole), Graphene oxide, Binuclear phthalocyanine cobalt(II) sulphonate, Quinoxaline-2-carboxylic acid