Inventors: Dong F, Xu WK, Chen XF
Patent Title: Preparing method for protein-binding-toxin-imprinted silica gel absorber and adsorption device
Publication date: 2018
Publication number: CN107955171A

Abstract: The invention relates to a preparing method for protein-binding-toxin-imprinted silica gel absorber and an adsorption device. The preparing method includes the following steps that 1, siloxane monomers are mixed and evenly dispersed under the conditions of the temperature lower than the normal temperature and the nitrogen atmosphere; 2, silica gel is activated and loaded with a pore-foaming agent,and is evenly dispersed in the mixture obtained in the step 1; 3, a protein-binding-toxin solution is rapidly and evenly dispersed in the mixture obtained in the step 2, a to-be-reacted solution is obtained, then acid is added, and a reaction is carried out; 4, the mixture obtained in the step 3 is filtered, washed, dried and calcined, and then the protein-binding-toxin-imprinted silica gel absorber is obtained. The preparing method is simple, the protein-binding-toxin-imprinted silica gel absorber is high in toxin adsorption rate, and is particularly suitable for uremia blood perfusion.
URL: https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20180424&DB=EPODOC&locale=en_EP&CC=CN&NR=107955171A&KC=A&ND=1