Abstract: Bisphenol A (BPA) interfered with the reproduction and endocrine system of humans and wild animals through eating way. For the detection of BPA, a sensitive and rapid detection method was established. BPA was imprinted on the surface of Fe3O4 nanoparticles through dopamine self-polymerization. After the removal of BPA, molecularly imprinted microspheres with BPA recognition cavity were formed. The electrochemical impedance response increased with BPA embedded in the molecular imprinting layer. The electrochemical signal was proportional to the concentration of BPA with a linear range from 1 x 10-11 to 1 x 10-3 M and a detection limit of 5.78 x 10-12 M. The proposed biosensor was used to detect the BPA in vegetable oil indicating a promising application in food-field monitoring
Author keywords: Bisphenol A, Polydopamine, molecular imprinted microspheres, Electrochemical impedance spectroscopy, Detection