Authors: Shutov RV
, Guerreiro A
, Moczko E
, de Vargas-Sansalvador IP
, Chianella I
, Whitcombe MJ
, Piletsky SA
Introducing MINA - The Molecularly Imprinted Nanoparticle Assay.
Publication date: 2014
Abstract: A new ELISA-(enzyme-linked immunosorbent assay)-like assay is demonstrated in which no elements of biological origin are used for molecular recognition or signaling. Composite imprinted nanoparticles that contain a catalytic core and which are synthesized by using a solid-phase approach can simultaneously act as recognition/signaling elements, and be used with minimal modifications to standard assay protocols. This assay provides a new route towards replacement of unstable biomolecules in immunoassays
Template and target information: vancomycin
Author keywords: molecular imprinting, core-shell materials, peroxidases, solid-phase synthesis
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