Authors: Skudar K
, Brüggemann O
, Wittelsberger A
, Ramström O
Selective recognition and separation of b-lactam antibiotics using molecularly imprinted polymers.
Publication date: 1999
Journal: Analytical Communications
Abstract: Molecularly imprinted polymers (MIPs) to penicillin V or oxacillin were prepared, and their recognition properties were investigated, both in organic and aqueous phases. The resulting MIPs proved to be efficient in distinguishing between different penicillins (penicillin V, penicillin G and oxacillin), but could also be prepared to recognise the penicillins as a group. The results indicate that MIPs can be used to prepare either selective or general recognition matrices for penicillins, which can be of potential use in separation and detection applications
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