Abstract: β-Cyclodextrin and epichlorohydrin were respectively used as functional monomer and cross-linker to synthesize molecularly imprinted polymers microspheres (MIPs) by suspension polymerization, for adsorption of paeoniflorin (PF), named PF-MIPs. The experiment indicated the PF-MIPs have specific selectivity on paeoniflorin. The paeoniflorin binding site was found inside of PF-MIPs by Scatchard analysis, with Kd and Qmax of 0.46 mg/mL and 47.22 mg/g, respectively. The adsorption process was endothermic process, the adsorption of paeoniflorin on MIPs followed Freundlich adsorption model. The PF-MIPs can be re-used to isolation paeoniflorin at least 10 times.
Template and target information: paeoniflorin
Author keywords: Molecularly imprinted polymers, Paeoniflorin, adsorption, β-cyclodextrin