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Reference type: Journal
Authors: Shiraki Y, Tsuruta K, Morimoto J, Ohba C, Kawamura A, Yoshida R, Kawano R, Uragami T, Miyata T
Article Title: Preparation of Molecule-Responsive Microsized Hydrogels via Photopolymerization for Smart Microchannel Microvalves.
Publication date: 2015
Journal: Macromolecular Rapid Communications
Volume: 36
Issue: (6)
Page numbers: 515-519.
DOI: 10.1002/marc.201400676

Abstract: Microdevices designed for practical environmental pollution monitoring need to detect specific pollutants such as dioxins. Bisphenol A (BPA) has been widely used as a monomer for the synthesis of polycarbonate and epoxy resins. However, the recent discovery of its high potential ability to disrupt human endocrine systems has made the development of smart systems and microdevices for its detection and removal necessary. Molecule-responsive microsized hydrogels with β-cycrodextrin (β-CD) as ligands are prepared by photopolymerization using a fluorescence microscope. The molecule-responsive micro-hydrogels show ultra-quick shrinkage in response to target BPA. Furthermore, the flow rate of a microchannel is autonomously regulated by the molecule-responsive shrinking of their hydrogels as smart microvalves
Template and target information: bisphenol A, BPA
Author keywords: dynamic cross-link, microchannels, Microfluidics, molecular recognition, stimuli-responsive hydrogels

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