Abstract: Molecularly imprinted polymers (MIPs) are generally synthesised either by thermal initiation or by photo polymerisation methods. Recently we used a gamma irradiation method for the preparation of MIPs. In this communication we compare three different methods for the synthesis of 2-hydroxy ethyl methacrylate (HEMA) based MIP imprinted for hydrocortisone in terms of its capacity to adsorb the print molecule. Our results show that MIP prepared by the gamma irradiation method has a better adsorption capacity than the thermally initiated polymer. It is interesting to note that its adsorption capacity is comparable or marginally better than the photo polymerised MIP
Template and target information: hydrocortisone