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Reference type: Journal
Authors: Zhang QW, Ren YM, Wei TX
Article Title: Surface plasmon resonance sensor combining with molecularly imprinted film for progesterone detection.
Publication date: 2015
Journal: Transaction of Beijing Institute of Technology
Volume: 35
Issue: (2)
Page numbers: 208-212.
DOI: 10.15918/j.tbit1001-0645.2015.02.019

Abstract: A surface plasmon resonance (SPR) sensor based on molecularly imprinted film (MIF) was proposed for the sensitive detection of progesterone. The MIF was synthesized by the method of thermo and photo polymerization on the sensor surface, which was subsequently removed to form the recognition cavities by the mixture of acetonitrile and acetic acid. The SPR sensor develops the angle shift by 1.15 (thermo polymerization) and 0.72 (photo polymerization) after washing progesterone from MIF and allowed detection of progesterone at concentration down to 10-14 g/mL. The resonance angle changes show a good linearity versus minus logarithmic concentration of progesterone from 10-14 g/mL to 10-6 g/mL. A control experiment with the analogues estradiol, testosterone and testosterone propionate (10-4 g/mL) shows a good selectivity of the MIF for the recognition of progesterone. , 2015, Beijing Institute of Technology. All right reserved.
Template and target information: progesterone
Author keywords: Molecularly imprinted film (MIF), Progesterone, surface plasmon resonance (SPR)


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