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Reference type: Journal
Authors: Jia XH, Tan N, Cheng Y, Zhang W, Yan XM, Li XL
Article Title: Design, preparation, surface recognition properties, and characteristics of icariin molecularly imprinted polymers.
Publication date: 2015
Journal: Cogent Chemistry
Volume: 1
Issue: (1)
Page numbers: 1059597.
DOI: 10.1080/23312009.2015.1059597

Abstract: Icariin molecularly imprinted polymers (MIPs) were prepared by precipitation polymerization. Prior to the polymerization, computer simulation was performed to sketchily choose the suitable functional monomer and the corresponding polymerization solvent. The optimized synthesis parameters, including the functional monomer acrylamide, the mixture of methanol and acetonitrile (V:V = 3:1) as the polymerization solvent, and the reaction molar ratio (1:6:80) of template molecule, functional monomer and cross-linker, were respectively obtained by single factor analysis and orthogonal design methods. The results of the adsorption experiments showed that the resultant MIPs exhibited good adsorption and recognition abilities to icariin. Scatchard analysis illustrated that the homogeneous binding sites only for icariin molecules were formed in the prepared MIPs
Template and target information: icariin
Author keywords: Preparation, adsorption, Recognition, icariin, molecularly imprinted polymers (MIPs)

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