MIPs logo MIPdatabase      MIP2020 Conference logo Use this space
Custom Search
Reference type: Journal
Authors: Gholivand MB, Torkashvand M
Article Title: The fabrication of a new electrochemical sensor based on electropolymerization of nanocomposite gold nanoparticle-molecularly imprinted polymer for determination of valganciclovir.
Publication date: 2016
Journal: Materials Science and Engineering: C
Volume: 59
Page numbers: 594-603.
DOI: 10.1016/j.msec.2015.09.016
Alternative URL: http://www.sciencedirect.com/science/article/pii/S0928493115303386

Abstract: A new sensitive and selective electrochemical sensor was successfully developed for the determination of valganciclovir. It is based on one-step electropolymerization of the molecularly imprinted polymer composed from 2,2'-dithiodianiline, gold nanoparticles, and valganciclovir on a glassy carbon electrode modified with carboxyl-functionalized multiwalled carbon nanotubes via cyclic voltammetry. The gold nanoparticles were introduced into the polymer composite for the development of electrical response by facilitating charge transfer. The fabrication process of the sensor was characterized by cyclic voltammetry and electrochemical impedance spectroscopy. Under the optimized condition calibration curve of the imprinted sensor has two linear concentration ranges from 1.0 to 500.0 nM and 500.0 to 2000.0 nM, with the limit of detection of 0.3 nM. The relative standard deviation (RSD) for seven parallel determination of 1.0 μM valganciclovir at optimum conditions was found to be 2.9%. The imprinted sensor has the advantages of high porous surface structure, ease of preparation, good reproducibility, good repeatability and high selectivity and sensitivity. Furthermore, the proposed method was successfully intended for the determination of valganciclovir in real samples
Template and target information: valganciclovir
Author keywords: Valganciclovir, molecularly imprinted polymer, Drug monitoring, electropolymerization, Au nanoparticles

  Eat, sleep, imprint, repeat greetings card  SMI logo mug  Man of proper-tea mug in blue

Molecules Special Issue call      Appeal for information


Join the Society for Molecular Imprinting
Logo of the Society for Molecular Imprinting

New items RSS feed
new items RSS feed  View latest updates

Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.

Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
Other products you may like:
view listings for MIP books on eBay:

Mickey Mouse 90th Anniversary banner