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Reference type: Journal
Authors: Chen YQ, Liu Y, Shen XD, Chang ZM, Tang LH, Dong WF, Li MY, He JJ
Article Title: Ultrasensitive Detection of Testosterone Using Microring Resonator with Molecularly Imprinted Polymers.
Publication date: 2015
Journal: Sensors
Volume: 15
Issue: (12)
Page numbers: 31558-31565.
DOI: 10.3390/s151229877
Alternative URL: http://www.mdpi.com/1424-8220/15/12/29877

Abstract: We report ultrasensitive and highly selective detection of testosterone based on microring resonance sensor using molecularly imprinted polymers (MIP). A silicon-on-insulator (SOI) micoring resonator was modified by MIP films (MIPs) on a surface. The MIPs was synthesized by thermopolymerization using methacrylic acid as functional monomer and ethylene glycol dimethacrylate as crosslinking agent. The concentration of detected testosterone varies from 0.05 ng/mL to 10 ng/mL. The detection limit reaches 48.7 pg/mL. Ultrahigh sensitivity, good specificity and reproducibility have been demonstrated, indicating the great potential of making a cost effective and easy to operate lab-on-Chip and down scaling micro-fluidics devices in biosensing.
Template and target information: testosterone
Author keywords: Microring resonator, Molecularly imprinted polymers, testosterone


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