MIPs logo MIPdatabase      MIP2018 Conference website
Custom Search
Reference type: Journal
Authors: Tomioka Y, Kudo Y, Hayashi T, Nakamura H, Niizeki M, Hishinuma T, Mizugaki M
Article Title: Phenobarbital molecularly imprinted polymer selectively binds phenobarbital.
Publication date: 1997
Journal: Biological & Pharmaceutical Bulletin
Volume: 20
Issue: (4)
Page numbers: 397-400.
DOI: 10.1248/bpb.20.397
Alternative URL: https://www.jstage.jst.go.jp/article/bpb1993/20/4/20_4_397/_article

Abstract: Molecularly imprinted polymer (MIP) was prepared against phenobarbital using methacrylic acid as the functional monomer and ethylene glycol dimethacrylate as the cross linking monomer. We analyzed the recognition properties of the phenobarbital MIP. In some organic solvents, imprinted polymer showed selective binding to phenobarbital. Two dissociation constants of binding were calculated by Scatchard plot analyses; K-d values were 1.8, 121.7 μM, and the number of binding sites was 8.3, 92.3 μmol/g MIP in toluene- heptane-acetic acid (25:75:1, v/v), respectively. The relationship between the binding affinity to phenobarbital MIP and the polarity of the solvent system, as well as the structure of the template molecule is also discussed
Template and target information: phenobarbital


  Template of Doom spoof movie poster shirt  Chemistry peptide mug  Chemists are fun customisable shirt

Molecules Special Issue call     Sensors Special Issue call






Join the Society for Molecular Imprinting
Logo of the Society for Molecular Imprinting

New items RSS feed
new items RSS feed  View latest updates

Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.


Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
Other products you may like:
view listings for MIP books on eBay:
US listings   UK listings

Searching for Molecular Imprinting books on Amazon.com:
Molecular Imprinting
Imprinted Polymers
Polymer Chemistry
Organic Chemistry
Biosensors

Find what you need at Amazon.com

Lab supplies from Amazon