MIPs logo MIPdatabase      Use this space
Custom Search
Reference type: Journal
Authors: Li XX, Mei XL, Xu L, Shen X, Zhu WY, Hong JL, Zhou XM
Article Title: Development and application of novel clonazepam molecularly imprinted coatings for stir bar sorptive extraction.
Publication date: 2016
Journal: Journal of Colloid and Interface Science
Volume: 468
Page numbers: 183-191.
DOI: 10.1016/j.jcis.2016.01.072
Alternative URL: http://www.sciencedirect.com/science/article/pii/S0021979716300728

Abstract: The molecularly imprinted magnetic stir bar coatings were created based on graft-functional Fe3O4 nanoparticles with magnetic field-induced self-assembly. The magnetic complex including clonazepam as template, the graft-functional Fe3O4 nanoparticles and methacrylic acid as monomers was pre-assembled through π-π interaction and hydrogen bonding, then was directionally adsorbed on the surface of magnetic stir bar under the magnetic induction. The molecularly imprinted coating with well-ordered structure was generated by one-step copolymerization based on the cross linking of ethylene glycol dimethacrylate. The molecularly imprinted coating with multiple recognition sites could be manufactured and applied in polar solvents, and showed superior selectivity and fast binding kinetics for benzodiazepines. The analytes in herbal health foods, treated by stir bar sorptive extraction, were determined by HPLC-UV. Good linearity was observed in the range of 0.01-2 μg mL-1. The content of clonazepam in the herbal health foods was found to be 44 ng g-1, and the average recoveries were 89.8-103.3% with a relative standard deviation (RSD) < 6.5%, demonstrating the successful application in real sample analysis
Template and target information: clonazepam
Author keywords: Molecularly imprinted polymers, Graft-functional Fe3O4 nanoparticles, Magnetic field-induced self-assembly, HPLC-UV


  mipdatabase.com logo special offer joke shirt  Lab Honey Periodic table mug  HE-MAN polymer chemistry shirt

Molecules Special Issue call      Appeal for information






 

Join the Society for Molecular Imprinting
Logo of the Society for Molecular Imprinting

New items RSS feed
new items RSS feed  View latest updates

Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.


Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
Other products you may like:
view listings for MIP books on eBay:



Mickey Mouse 90th Anniversary banner