MIPs logo MIPdatabase      Use this space
Custom Search
Reference type: Journal
Authors: Kaamyabi S, Habibi D, Amini MM
Article Title: Preparation and characterization of the pH and thermosensitive magnetic molecular imprinted nanoparticle polymer for the cancer drug delivery.
Publication date: 2016
Journal: Bioorganic & Medicinal Chemistry Letters
Volume: 26
Issue: (9)
Page numbers: 2349-2354.
DOI: 10.1016/j.bmcl.2016.03.020
Alternative URL: http://www.sciencedirect.com/science/article/pii/S0960894X16302402

Abstract: A novel pH and thermosensitive magnetic nanoparticle polymer composite [poly(NIPAAM@Fe3O4 MNPs/TMSPMC/DOX)] was synthesized by radical polymerization of N-isopropylacrylamide (NIPAAM) and the methacrylate functionalized Fe3O4 nanoparticles/DOX complex using AIBN and EGDMA, and used as a drug carrier for the DOX drug delivery. Formation of poly(NIPAAM@Fe3O4 MNPs/TMSPMC/DOX) was confirmed by FTIR, XRD, UV-Vis, VSM, TGA-DTA and SEM. The results showed the high DOX loading controls release. Moreover, it showed the lower critical solution temperature of 40 C which can be beneficial in cancer drug delivery, since the temperature of cancer cells is higher than normal ones, and DOX can be released selectively in cancer cells
Template and target information: doxorubicin, DOX
Author keywords: Fe3O4 magnetic nanoparticles, Cancer drug delivery, doxorubicin, pH and thermosensitive composite

  Scandium periodic table greetings card  Scientist peptide mug  I shop perodically customisable tote bag

Molecules Special Issue call      Appeal for information


Join the Society for Molecular Imprinting
Logo of the Society for Molecular Imprinting

New items RSS feed
new items RSS feed  View latest updates

Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.

Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
Other products you may like:
view listings for MIP books on eBay:

Mickey Mouse 90th Anniversary banner