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Reference type: Journal
Authors: Templier V, Roux A, Roupioz Y, Livache T
Article Title: Ligands for label-free detection of whole bacteria on biosensors: A review.
Publication date: 2016
Journal: TrAC Trends in Analytical Chemistry
Volume: 79
Page numbers: 71-79.
DOI: 10.1016/j.trac.2015.10.015
Alternative URL: http://www.sciencedirect.com/science/article/pii/S0165993615301163

Abstract: With the aim of getting earlier, sensitive and specific information on the presence -or absence - of bacterial pathogens, biosensors are getting an increasing interest for more than two decades. This is partly due to their reduced format, to the possibility to address several questions with a single device and also to the increasing panel of physical approaches that can be exploited for signal transducing. When designing a biosensor, the choice of the ligand motif remains a key element as it drives the efficiency and sensitivity of the assay. In this review, we propose to gather and comment different ligands used for the detection of whole cell bacteria. Because time is a crucial issue when looking for a pathogen, our attention was focused on whole cell assays and label-free methods, which enable the user to skip sampling processing steps and decrease the overall test cost
Template and target information: Review - biosensors for bacteria
Author keywords: Bacterial pathogens, biosensor, ligands, Whole-bacteria detection, label-free

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