MIPs logo MIPdatabase      MIP2020 Conference logo Use this space
Custom Search
Reference type: Journal
Authors: Huang HL, Wang XH, Ge H, Xu M
Article Title: Multifunctional Magnetic Cellulose Surface-Imprinted Microspheres for Highly Selective Adsorption of Artesunate.
Publication date: 2016
Journal: ACS Sustainable Chemistry & Engineering
Volume: 4
Issue: (6)
Page numbers: 3334-3343.
DOI: 10.1021/acssuschemeng.6b00386

Abstract: Molecularly imprinted magnetic cellulose microspheres (MIP-MCM) of artesunate (Ars) are developed by a surface functional monomer-directing system. MIP-MCM are obtained by coating a layer of MIP on the surface of the cellulose and Fe3O4 composite microspheres. The composite materials are characterized by Fourier transform infrared spectra (FTIR), X-ray powder diffraction (XRD), vibrating sample magnetometry (VSM), UV-vis spectrophotometry (UV), dynamic light scattering (DLS), and magnetic resonance imaging (MRI). They are adsorption-selective to Ars, highly regenerate, and stable in wide pH and temperature ranges. The adsorption of Ars reaches equilibrium within 10 h, and the maximum adsorption quantity is as high as 0.22 mg/mg, much better than previous reports. Through the Langmuir-Freundlich isotherm and pseudo-second-order kinetic model, the adsorption kinetics and thermodynamics of MIP-MCM were studied. The thermodynamic studies suggest that the adsorption of Ars on MIP-MCM is a spontaneous process. MIP-MCM also show rapid magnetic separation and high reusability (retained 90% after five cycles). Thus, it is an efficient method for Ars separation and purification. Furthermore, MIP-MCM are good negative MRI contrast agents with good biocompatibility. Due to these properties, this work offers a new potential application for MIP-MCM in aspects of drug delivery and tracking, disease diagnosis, and therapy
Template and target information: artesunate, Ars
Author keywords: Molecularly imprinted polymers, Magnetic cellulose microspheres, Artesunate, imaging, Releasing


  Periodic table Vindaloo - the chemical formula for curry shirt  Periodic table Bag bag  Meerkat somebody mention coffee mug

Molecules Special Issue call      Appeal for information






 

Join the Society for Molecular Imprinting
Logo of the Society for Molecular Imprinting

New items RSS feed
new items RSS feed  View latest updates

Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.


Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
Other products you may like:
view listings for MIP books on eBay:



Mickey Mouse 90th Anniversary banner