Abstract: Preparation of uniform size molecularly imprinted nanospheres (MIPMs) from the electron beam radiation of functional monomer( methacrylic acid) and crosslinking agent( ethylene glycol dimethacrylate) in the presence of chloramphenicol as template. The characterization of MIPMs can be achieved by FT-IR and static nitrogen adsorption.The results indicate the template molecule could be fixed in molecularly imprinted polymer and the largest specific area is 280.25 m2/g. The effect of radiation dose on the morphology and binding capacity of MIPMs was studied by SEM and isothermal adsorption experiments. The results show that MIPMs prepared under the condition of 20 kGy radiation dose exhibit spherical shape and the max adsorption amount of chloramphenicol reaches 107. 65 μmol /g. The separation factors are 3. 08 and 4. 66, respectively.
Template and target information: chloramphenicol