Abstract: In the present work, antibiotic drug Amikacin has been used as template molecule to prepare poly(methacrylic acid) based molecularly imprinting polymer (MIP), using acetonitrile (Acn) as porogenic solvent. The MIP has been used for the selective removal of drug Amikacin (Amk) using column mode operation. The removal efficiency of the MIP was found to increase with the length of the column, while the increase in the flow rate was found to decrease the extent of removal. In addition, increase in the concentration of the feed drug solution also enhanced the extent of removal. The kinetic drug removal data was interpreted in the terms of various models such as Thomas and Yoon-Nelson models
Template and target information: amikacin, Amk
Author keywords: Amikacin, column mode, Flow rate, Thomas model