MIPdatabase
Authors: Abbasifar J, Samadi-Maybodi A
Article Title: Selective Determination of Atropine Using poly Dopamine-Coated Molecularly Imprinted Mn-Doped ZnS Quantum Dots.
Publication date: 2016
Journal: Journal of Fluorescence
Volume: 26
Issue: (5)
Page numbers: 1645-1652.
DOI: 10.1007/s10895-016-1853-9
Abstract: In this study, a selective method for the determination of atropine in pharmaceutical formulations was proposed. L-cysteine capped Mn-doped ZnS quantum dots (QDs) were prepared in an in-situ method using sodium thiosulfate precursor and characterized by spectrofluorometer, Fourier transform infrared spectroscopy (FT-IR), transmission electron microscope (TEM) and X-ray diffractometer (XRD). Dopamine hydrochloride was used as a precursor for preparation of poly dopamine-coated molecularly imprinted Mn-doped ZnS quantum dots. Finally, these prepared molecularly imprinted Mn-doped ZnS quantum dots were used for determination of atropine in pharmaceutical formulations. The obtained linear range for determination of atropine was in the range of 2 x 10-8 - 7 x 10-6 M, with a correlation coefficient (R2) of 0.9889; and the detection limit (S/N = 3) was 3.2 nM
Template and target information: atropine
Author keywords: Atropine, Molecularly imprinted polymers, Quantum dots, Polydopamine, n-dopped ZnS
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