MIPs logo MIPdatabase      Use this space
Custom Search
Reference type: Journal
Authors: Vergara AV, Pernites RB, Tiu BDB, de Leon ACC, Mangadlao JD, Binag CA, Advincula RC
Article Title: Capacitive Detection of Morphine via Cathodically Electropolymerized, Molecularly Imprinted Poly(p-aminostyrene) Films.
Publication date: 2016
Journal: Macromolecular Chemistry And Physics
Volume: 217
Issue: (16)
Page numbers: 1810-1822.
DOI: 10.1002/macp.201600127

Abstract: Highly sensitive and selective detection of morphine is exhibited using a capacitive transducer coated with cathodically electropolymerized and molecularly imprinted poly(p aminostyrene). Through molecular imprinting, morphine-specific recognition sites have been fabricated throughout the film, which shows exceptional binding activity toward morphine based from electrochemical capacitance measurements. The thin film sensor has a linear response to morphine solutions with 20-40 x 10-6 m concentrations and a detection limit of 5.95 x 10-6 m. It demonstrates high selectivity toward morphine as compared to other analog molecules including nicotine and cholesterol. The formation of the polymer film is facilitated and monitored using electrochemical-quartz crystal microbalance and characterized by X-ray photoelectron spectroscopy. Infrared spectroscopy confirms the loading and removal of the analyte from the film. Based on molecular modeling calculations, strong hydrogen-bonding interactions between the monomer, cross-linker, and analyte form a stable pre-polymerization complex, which is critical in successfully imprinting morphine into the film and effective sensing of the analyte
Template and target information: morphine
Author keywords: capacitive detection, electropolymerization, molecular imprinting, morphine, p-Aminostyrene


  I love MISPE bag  multi MIPs logo mug  British periodic table patriotic tote bag

Molecules Special Issue call      Appeal for information






 

Join the Society for Molecular Imprinting
Logo of the Society for Molecular Imprinting

New items RSS feed
new items RSS feed  View latest updates

Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.


Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
Other products you may like:
view listings for MIP books on eBay:



Mickey Mouse 90th Anniversary banner