MIPs logo MIPdatabase      MIP2020 Conference logo Use this space
Custom Search
Reference type: Journal
Authors: Amjadi M, Jalili R
Article Title: Molecularly imprinted polymer-capped nitrogen-doped graphene quantum dots as a novel chemiluminescence sensor for selective and sensitive determination of doxorubicin.
Publication date: 2016
Journal: RSC Advances
Volume: 6
Issue: (89)
Page numbers: 86736-86743.
DOI: 10.1039/C6RA18184H

Abstract: In this work, molecularly imprinted polymer-capped nitrogen-doped graphene quantum dots (MIP@NGQDs) were prepared via a simple sol-gel process and used for recognition of the anti-cancer drug, doxorubicin. Strong chemiluminescence (CL) emission was observed when potassium permanganate was injected into the solution of MIP@NGQDs. At the same time, in the presence of doxorubicin the CL intensity was significantly quenched and this was exploited to develop a CL detection scheme for this drug. The mechanism of the MIP@NGQDs/KMnO4 CL system was investigated by recording UV-Vis, fluorescence and CL spectra. Under the optimal conditions, the relative CL intensity linearly decreased with the concentration of doxorubicin in the range of 20-260 μg L-1. The limit of detection was 4.7 μg L-1. The method was applied to the determination of therapeutic levels of doxorubicin in spiked serum samples with satisfactory results
Template and target information: doxorubicin


  Double Bonds spoof movie poster mug  Chemistry peptide mug  Chemists are fun customisable shirt

Molecules Special Issue call      Appeal for information






 

Join the Society for Molecular Imprinting
Logo of the Society for Molecular Imprinting

New items RSS feed
new items RSS feed  View latest updates

Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.


Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
Other products you may like:
view listings for MIP books on eBay:



Mickey Mouse 90th Anniversary banner