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Reference type: Journal
Authors: Kim S, Wang N, Li YJ, He XW
Article Title: Electrochemical determination of mesalazine by using graphene oxide coated with a molecularly imprinted sol-gel.
Publication date: 2016
Journal: Analytical Methods
Volume: 8
Issue: (43)
Page numbers: 7780-7788.
DOI: 10.1039/C6AY02243J

Abstract: Graphene oxide coated with a molecularly imprinted sol-gel was prepared by one-pot synthesis from phenyltriethoxysilane and tetramethoxysilane. The composite modified electrode was used for electrochemical determination of mesalazine (ASA) by differential pulse voltammetry (DPV) in Britton-Robinson buffer solution (pH = 2.0). The peak current was linear with the concentration in the range from 2 to 20 μmol L-1 (r2 = 0.9955) and 20 to 150 μmol L-1 (r2 = 0.9987) with a detection limit of 0.97 μmol L-1 (S/N = 3). Interferents with similar structures such as salicylic acid, 4-aminophenol, 2-aminobenzoic acid and 4-acetamidophenol were examined. The utilizability and reliability of this method were confirmed by the determination of mesalazine in a drug tablet
Template and target information: mesalazine, ASA

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