MIPs logo MIPdatabase      Use this space
Custom Search
Reference type: Journal
Authors: Ben Aissa A, Herrera-Chacon A, Pupin RR, Sotomayor MDPT, Pividori MI
Article Title: Magnetic molecularly imprinted polymer for the isolation and detection of biotin and biotinylated biomolecules.
Publication date: 2017
Journal: Biosensors and Bioelectronics
Volume: 88
Page numbers: 101-108.
DOI: 10.1016/j.bios.2016.07.096
Alternative URL: http://www.sciencedirect.com/science/article/pii/S0956566316307266

Abstract: Magnetic separation based on biologically-modified magnetic particles is a preconcentration procedure commonly integrated in magneto actuated platforms for the detection of a huge range of targets. However, the main drawback of this material is the low stability and high cost. In this work, a novel hybrid molecularly-imprinted polymer with magnetic properties is presented with affinity towards biotin and biotinylated biomolecules. During the synthesis of the magneto core-shell particles, biotin was used as a template. The characterization of this material by microscopy techniques including SEM, TEM and confocal microscopy is presented. The application of the magnetic-MIPs for the detection of biotin and biotinylated DNA in magneto-actuated platforms is also described for the first time. The magnetic-MIP showed a significant immobilization capacity of biotinylated molecules, giving rise to a cheaper and a robust method (it is not required to be stored at 4 C) with high binding capacity for the separation and purification under magnetic actuation of a wide range of biotinylated molecules, and their downstream application including determination of their specific targets
Template and target information: biotin, biotinylated biomolecules
Author keywords: magnetic particles, magnetic molecularly-imprinted polymer, biotinylated biomolecules, magneto-actuated immunoassay, immunomagnetic separation


  MIPs are Forever spoof movie poster mug  Mug featuring the name Maria spelled out in the single letter amino acid code  Chemists are fun customisable shirt

Molecules Special Issue call      Appeal for information






 

Join the Society for Molecular Imprinting
Logo of the Society for Molecular Imprinting

New items RSS feed
new items RSS feed  View latest updates

Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.


Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
Other products you may like:
view listings for MIP books on eBay:



Mickey Mouse 90th Anniversary banner