MIPs logo MIPdatabase      MIP2020 Conference logo Use this space
Custom Search
Reference type: Journal
Authors: Kim DM, Moon JM, Lee WC, Yoon JH, Choi CS, Shim YB
Article Title: A potentiometric non-enzymatic glucose sensor using a molecularly imprinted layer bonded on a conducting polymer.
Publication date: 2017
Journal: Biosensors and Bioelectronics
Volume: 91
Page numbers: 276-283.
DOI: 10.1016/j.bios.2016.12.046
Alternative URL: https://www.researchgate.net/publication/312405499_A_potentiometric_non-enzymatic_glucose_sensor_using_a_molecularly_imprinted_layer_bonded_on_a_conducting_polymer

Abstract: A non-enzymatic potentiometric glucose sensor for the determination of glucose in the micomolar level in saliva was developed based on a molecularly imprinted polymer (MIP) binding on a conducting polymer layer. A MIP containing acrylamide, and aminophenyl boronic acid, as a host molecule to glucose, was immobilized on benzoic acid-functionalized poly(terthiophene) (pTBA) by the amide bond formation onto a gold nanoparticles deposited-screen printed carbon electrode (pTBA/AuNPs/SPCE). Aromatic boronic acid was incorporated into the MIP layer to stably capture glucose and create a potentiometric signal through the changed pKa value of polymer film by the formation of boronate anion-glucose complex with generation of H+ ions by the cis-diol reaction. Reversible binding and extraction of glucose on the sensor surface was observed using a quartz crystal microbalance. Each layer of the sensor probe was characterized by cyclic voltammetry, electrochemical impedance spectroscopy, X-ray photoelectron spectroscopy, and atomic force microscopy. The potentiometric response at the optimized conditions exhibited a wide linear dynamic range of 3.2 x 10-7 to 1.0 x 10-3 M, with a detection limit of 1.9 (0.15) x 10-7 M. The sensor probe revealed an excellent selectivity and sensitivity for glucose compared to other saccharides. In addition, the reliability of the proposed glucose sensor was evaluated in physiological fluid samples of saliva and finger prick blood
Template and target information: glucose
Author keywords: conducting polymer, molecularly imprinted polymer, Aminophenyl boronic acid, glucose, potentiometric sensor

  Periodic table Prof shirt  PhD Scientist peptide mug  We need to talk about Kelvin shirt

Molecules Special Issue call      Appeal for information


Join the Society for Molecular Imprinting
Logo of the Society for Molecular Imprinting

New items RSS feed
new items RSS feed  View latest updates

Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.

Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
Other products you may like:
view listings for MIP books on eBay:

Mickey Mouse 90th Anniversary banner