MIPs logo MIPdatabase      Use this space
Custom Search
Reference type: Journal
Authors: Prasad BB, Singh K
Article Title: Molecularly imprinted polymer-based core-shells (solid vs hollow) @ pencil graphite electrode for electrochemical sensing of certain anti-HIV drugs.
Publication date: 2017
Journal: Sensors and Actuators B: Chemical
Volume: 244
Page numbers: 167-174.
DOI: 10.1016/j.snb.2016.12.109
Alternative URL: http://www.sciencedirect.com/science/article/pii/S0925400516320809

Abstract: The present work describes a new, simple, and easy method for the fabrication of molecularly imprinted polymer-based core-shells (solid and hollow) @ pencil graphite electrode for sensing anti-HIV drugs, lamivudine and zidovudine, in real samples. For this, an imprinted polymer was developed on the surface of vinylated silica nanospheres to obtain modified solid as well as hollow core-shells. In this work, respective electrodics in terms of analyte diffusion for binding and electrode kinetics of both modified solid and hollow core-shells were compared using a ferricyanide probe with cyclic voltammetric and differential pulse anodic stripping voltammetric methods of transduction. Whereas modified solid core-shells evolved unilateral diffusion of probe/analyte molecules, the corresponding hollow core-shells were found to be relatively better owing to their bilateral diffusions into molecular cavities. Indirect detections of electroinactive targets chosen were feasible with the help of probe using imprinted hollow core shells modified electrode with limits of detection as low as 2.23 and 1.26 (aqueous sample), 2.45 and 1.88 (blood serum), and 2.52 and 1.77 ng mL-1 (pharmaceutics) for lamivudine and zidovudine, respectively
Template and target information: anti-HIV drugs, lamivudine, zidovudine
Author keywords: Solid, hollow core-shells, Core-shells modified imprinted electrochemical sensors, Lamivudine, Zidovudine, Ferricyanide probe, Differential pulse anodic stripping voltammetry


  Mister Benzene Birthday card  Chemistry peptide mug  Beach bunny periodic table shirt

Molecules Special Issue call      Appeal for information






Join the Society for Molecular Imprinting
Logo of the Society for Molecular Imprinting

New items RSS feed
new items RSS feed  View latest updates

Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.


Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
Other products you may like:
view listings for MIP books on eBay:
US listings   UK listings

Searching for Molecular Imprinting books on Amazon.com:
Molecular Imprinting
Imprinted Polymers
Polymer Chemistry
Organic Chemistry
Biosensors

Find what you need at Amazon.com

Lab supplies from Amazon