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Reference type: Journal
Authors: Amiri A, Ramazani A, Jahanshahi M, Moghadamnia AA
Article Title: Synthesis and Evaluating of Nanoporous Molecularly Imprinted Polymers for Extraction of Quercetin as a Bioactive Component of Medicinal Plants.
Publication date: 2016
Journal: Iranian Journal of Chemistry and Chemical Engineering
Volume: 35
Issue: (4)
Page numbers: 11-19.
Alternative URL: http://www.ijcce.ac.ir/article_23550.html

Abstract: In this work, the template, monomer, and cross-linker with the ratio of 1:8:40 were used to synthesize Molecularly Imprinted Polymers (MIPs) for extraction of the bioactive chemical compounds from some traditional herbs as a sorbent material. Quercetin, Methacrylic Acid (MAA), Trimethylolpropanetrimethacrylate (TRIM) and Tetrahydrofuran (THF) were used as a template, functional monomer, cross-linker, and porogen, respectively. Polymer particles have been evaluated by Atomic Force Microscopy (AFM), Field Emission Scan Electron Microscopy (FESEM), Transmission Electron Microscopy (TEM) and Brunauer-Emmett-Teller (BET). The produced nanoporous MIPs, with a good specific surface area 167.899 m2/g comparatively to Non-Imprinted Polymers (NIPs), exhibited a good affinity to quercetin with the binding capacity of 392.08 mg/g in acetonitrile-water (1:1v/v). The results showed that the MIPs can be used as a sorbent. Thus, direct extraction of certain pharmacophoric components from herbal plants is considerable by MIPs technology.
Template and target information: quercetin
Author keywords: Molecularly imprinted polymers, quercetin, Medicinal plants, nanoporous, extraction, Bioactive

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