MIPs logo MIPdatabase      Use this space
Custom Search
Reference type: Journal
Authors: Yang YF, Cao XM, Li XL, Song JD, Sun XL, Wang ST, Wang XY, Li L, Zhao SJ
Article Title: Determination of nine fluoroquinolone residues in chicken by ultra performance liquid chromatography-tandem mass spectrometry coupled with molecularly imprinted solid phase extraction.
Publication date: 2016
Journal: Chinese Journal of Chromatography
Volume: 34
Issue: (11)
Page numbers: 1063-1069.
DOI: 10.3724/SP.J.1123.2016.07024
Alternative URL: http://www.chrom-china.com/EN/abstract/abstract14177.shtml

Abstract: An ultra performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) method coupled with molecularly imprinted solid phase extraction (MISPE) for the determination of nine fluoroquinolone residues in chicken was developed. The samples were extracted with phosphate buffer solution, and cleaned up with MISPE columns. Then the drugs were analyzed on a BEH C18 column by gradient elution with acetonitrile and 0.1% (v/v) formic acid solution as mobile phase. The samples were analyzed in electrospray positive ion mode and multiple reaction monitoring (MRM) mode. The analytes were quantified by external standard method. The specific adsorption of MISPE for the nine fluoroquinolones in chicken samples was investigated. The linear ranges were 0.25-100 μg/L with correlation coefficients (r) greater than 0.9965. The limits of detection (LODs, S/N=3) and the limits of quantification (LOQs, S/N=10) were 0.08 μg/kg and 0.25 μg/kg, respectively. At the spiked levels of 0.25, 2.5, 5.0 μg/kg, the recoveries were 65.8%-112.2% with the intra-RSDs of 0.6%-13.5% and inter-RSDs of 0.5%-14.9%, respectively. The maximum capacities of the MISPE column were 464.7-932.4 μg/L. The method is sensitive, simple and rapid for the simultaneous determination of the nine fluoroquinolone residues.
Template and target information: fluoroquinolines
Author keywords: ultra performance liquid chromatography-tandem mass spectrometry (UPLC-MS, MS), Molecularly imprinted solid phase extraction (MISPE), Fluoroquinolones, Chicken


  I love MIPs magnet  multi MIPs logo mug  Ireland periodic table shirt

Molecules Special Issue call      Appeal for information






 

Join the Society for Molecular Imprinting
Logo of the Society for Molecular Imprinting

New items RSS feed
new items RSS feed  View latest updates

Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.


Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
Other products you may like:
view listings for MIP books on eBay:



Mickey Mouse 90th Anniversary banner