Abstract: An electrochemical sensor based on melorcularly imprinted films for chlorogenic acid (CGA) detection is reported. The sensor was prepared by electropolemerizing o-phenylenediamine (OPD) on a glassy carbon electrode in the presence of template chlorogenic acid. Differential pulse voltammetry was applied to investigate the analytical characteristics of the sensor, and indirect analytical method based on K3[Fe(CN)6] which is as electron transfer medium was established. The results indicate that the method has high selectivity and sensitivity, the relative peak current of sensor shows a linear dependance on the concentration of chlorogenic acid in the range of 8.0 × 10-7 ~ 2.0 × 10-5 mol/L, with the detection limit of 1.4 × 10-7 mol/L. This sensor was successfully applied to determination of chlorogenic acid in qinggan lidan oral liquid samples with recoveries ranging from 101.6% to 105.5%.
Template and target information: chlorogenic acid, CGA
Author keywords: chlorogenic acid, o-phenylenediamine, molecularly imprinted polymer, Electrochemical sensor