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Abstract: The authors describe a voltammetric sensor for trace analysis of streptomycin (STR). It is based on the use of a glassy carbon electrode that was modified with a film of STR-imprinted poly(pyrrole-3-carboxy acid) (PPy3C) on electrochemically reduced graphene oxide (ERGO). ERGO was first deposited on the surface of GCE by electro-reduction, this followed by deposition of a film of STR-imprinted PPy3C. The morphologies and properties of the sensor were characterized by scanning electron microscopy, cyclic voltammetry, and differential pulse voltammetry. Under optimized conditions, the sensor for STR displays two linear ranges that cover the 2 to 80, and the 80 to 1000 nM concentration range. Other features include a 0.5 nM limit of detection, good molecular recognition, and reliable practicability. Results indicate that the method provides a promising biomimetic platform for the determination of STR in food such as porcine kidney and honey
Template and target information: streptomycin, STR
Author keywords: Aminoglycoside, Antibiotic, cyclic voltammetry, differential pulse voltammetry, molecularly imprinted polymer, conducting polymer, Hexacyanoferrate, scanning electron microscopy, Imprinted electrode, Kidney analysis, Honey analysis