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Reference type: Journal
Authors: Mehrzad-Samarin M, Faridbod F, Dezfuli AS, Ganjali MR
Article Title: A novel metronidazole fluorescent nanosensor based on graphene quantum dots embedded silica molecularly imprinted polymer.
Publication date: 2017
Journal: Biosensors and Bioelectronics
Volume: 92
Page numbers: 618-623.
DOI: 10.1016/j.bios.2016.10.047
Alternative URL: http://www.sciencedirect.com/science/article/pii/S0956566316310727

Abstract: A novel optical nanosensor for detection of Metronidazole in biological samples was reported. Graphene quantum dots embedded silica molecular imprinted polymer (GQDs-embedded SMIP) was synthesized and used as a selective fluorescent probe for Metronidazole detection. The new synthesized GQDs-embedded SMIP showed strong fluorescent emission at 450 nm excited at 365 nm which quenched in presence of Metronidazole as a template molecule. The quenching was proportional to the concentration of Metronidazole in a linear range of at least 0.2 μM to 15μM. The limit of detection for metronidazole determination was obtained 0.15 μM. The nanosensor successfully worked in plasma matrixes
Template and target information: metronidazole
Author keywords: Nanosensor, fluorescence detection, Graphene quantum dots, Metronidazole, molecularly imprinted polymer, Inorganic silica polymer


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