MIPs logo MIPdatabase      MIP2020 Conference logo Use this space
Custom Search
Reference type: Journal
Authors: Zhang XY, Zhang N, Du CB, Guan P, Gao XM, Wang CY, Du YF, Ding SC, Hu XL
Article Title: Preparation of magnetic epitope imprinted polymer microspheres using cyclodextrin-based ionic liquids as functional monomer for highly selective and effective enrichment of cytochrome c.
Publication date: 2017
Journal: Chemical Engineering Journal
Volume: 317
Page numbers: 988-998.
DOI: 10.1016/j.cej.2017.02.138
Alternative URL: http://www.sciencedirect.com/science/article/pii/S1385894717303182

Abstract: Epitope molecularly imprinted polymers (EMIPs) were synthesized using a novel cyclodextrin-based ionic liquid as functional monomer for specific recognition of cytochrome c (Cyt c) in aqueous solution via the combination of epitope and surface imprinting approach. Herein, the surface-exposed C-terminus of Cyt c (residues 96-104, AYLKKATNE) was selected as the template. Results reveal that the charged monomer cyclodextrins (CDs), namely mono-6A-deoxy-6-(1-vinylimidazolium)-β-cyclodextrin tosylate, could confer EMIPs with superior adsorption (67.6 mg g-1) and excellent recognition property (4.54) toward Cyt c due to its multiple binding sites with template such as hydrogen bonding, π-π effect, electrostatic, hydrophobic as well as steric effects. Moreover, the magnetic property of EMIPs has endowed the whole separation process with great convenience and efficiency, which demonstrated their potential application for large-scale separation and recognition
Template and target information: protein, peptide, epitope, AYLKKATNE, cytochrome c, Cyt c
Author keywords: Cyclodextrin-based ionic liquid, Epitope and surface imprinting, Multiple interactions, Magnetic property, Cytochrome C

  mipdatabase.com logo special offer joke shirt  Lab Chick Periodic table shirt  HE-MAN polymer chemistry shirt

Molecules Special Issue call      Appeal for information


Join the Society for Molecular Imprinting
Logo of the Society for Molecular Imprinting

New items RSS feed
new items RSS feed  View latest updates

Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.

Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
Other products you may like:
view listings for MIP books on eBay:

Mickey Mouse 90th Anniversary banner