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Authors: Gong CB, Li ZY, Liu LT, Wei YB, Yang X, Chow CF, Tang Q
Article Title: Photocontrolled extraction of uric acid from biological samples based on photoresponsive surface molecularly imprinted polymer microspheres.
Publication date: 2017
Journal: Journal of Separation Science
Volume: 40
Issue: (6)
Page numbers: 1396-1402.
DOI: 10.1002/jssc.201601243
Abstract: We aim to develop novel photoresponsive surface molecularly imprinted polymer (SIMP) microspheres, an SiO2-SIMP, for the photocontrolled extraction of uric acid from biological samples. The SiO2-SMIP was prepared on silica microspheres by surface polymerization and characterized by using scanning electron microscopy, transmission electron microscopy, FTIR spectroscopy, thermogravimetric analysis, nitrogen adsorption-desorption analysis, and UV-visible spectroscopy. The SiO2-SMIP microspheres showed a photocontrolled uptake and release of uric acid in NaH2PO4 buffer upon alternate irradiation at 365 and 440-ánm. The SiO2-SMIP microspheres were able to photocontrollably extract uric acid from complicated biological samples for concentration analysis with no significant interference encountered and it exhibited very good recognition ability and fast binding kinetics toward uric acid
Template and target information: uric acid
Author keywords: molecular imprinting, photocontrolled extraction, surface molecularly imprinted polymers, uric acid, urine
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