MIPs logo MIPdatabase      MIP2020 Conference logo Use this space
Custom Search
Reference type: Journal
Authors: Shen M, Rusling JF, Dixit CK
Article Title: Site-selective orientated immobilization of antibodies and conjugates for immunodiagnostics development.
Publication date: 2017
Journal: Methods
Volume: 116
Page numbers: 95-111.
DOI: 10.1016/j.ymeth.2016.11.010
Alternative URL: http://www.sciencedirect.com/science/article/pii/S1046202316304522

Abstract: Immobilized antibody systems are the key to develop efficient diagnostics and separations tools. In the last decade, developments in the field of biomolecular engineering and crosslinker chemistry have greatly influenced the development of this field. With all these new approaches at our disposal, several new immobilization methods have been created to address the main challenges associated with immobilized antibodies. Few of these challenges that we have discussed in this review are mainly associated to the site-specific immobilization, appropriate orientation, and activity retention. We have discussed the effect of antibody immobilization approaches on the parameters on the performance of an immunoassay
Template and target information: Review - immunodiagnostics
Author keywords: Site-selective, Site-specific, orientation, immobilization, antibody, Antibody fragments, click chemistry, Affinity tags, Protein A, Nucleotide binding protein, Metal binding protein, Staudinger ligation, cycloaddition, Antibody-binding protein, Physical adsorption, Diagnostics, Therapeutics, separation

  SMI cryptic logo shirt, new improved design  SMI logo mug  Woman of proper-tea mug

Molecules Special Issue call      Appeal for information


Join the Society for Molecular Imprinting
Logo of the Society for Molecular Imprinting

New items RSS feed
new items RSS feed  View latest updates

Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.

Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
Other products you may like:
view listings for MIP books on eBay:

Mickey Mouse 90th Anniversary banner