MIPs logo MIPdatabase      MIP2020 Conference logo Use this space
Custom Search
Reference type: Journal
Authors: Zhang XL, Luo YJ, Jiang J, Lu Y, Feng N
Article Title: Determination of five β2-agonist residues in pork by ultra-high performance liquid chromatography-tandem mass spectrometry with molecularly imprinted solid phase extraction.
Publication date: 2015
Journal: Chinese Journal of Chromatography
Volume: 33
Issue: (8)
Page numbers: 838-842.
DOI: 10.3724/SP.J.1123.2015.04016
Alternative URL: http://www.chrom-china.com/EN/abstract/abstract13923.shtml

Abstract: An ultra-high performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) method with molecularly imprinted solid phase extraction for the determination of five β2-gonists residues in pork has been developed. After the sample preparation, the ammonium acetate/acetic acid buffer was added, followed by the internal standard and β-glucuronidase/arylsulfatase enzyme. The solution was incubated at 55 C for 2 h. After adjusting the pH of the solution, it was purified by a molecularly imprinted solid phase extraction column, then analyzed on a BEH C18 column with methanol-0.1% (v/v) formic acid aqueous solution as the mobile phases in gradient elution mode. The MS/MS analysis was in positive ion mode and multiple reaction monitoring mode. The analytes were quantified by the internal standard method. The limits of detection (LODs, S/N=3) and the limits of quantification (LOQs, S/N=10) were 0.005-0.009 μg/kg and 0.015-0.025 μg/kg, respectively. In the range of 0-10 μg/kg, the correlation coefficients of linear calibration curves were not less than 0.9933. At the spiked levels of 0.25, 1.0 and 5.0 μg/kg, the recoveries were 80.4%-92.9% with the relative standard deviations of 1.3%-6.3%. The method is of high sensitivity, good reproducibility, high recovery, and is useful for the simultaneous determination of multiple β2-agonists residues.
Template and target information: β2-agonists
Author keywords: ultra-high performance liquid chromatography-tandem mass spectrometry (UPLC-MS, MS), molecularly imprinted solid phase extraction, β2-Agonists, residues, Pork


  mipdatabase.com logo special offer joke shirt  Lab Heroine Periodic bag  HE-MAN polymer chemistry shirt

Molecules Special Issue call      Appeal for information






 

Join the Society for Molecular Imprinting
Logo of the Society for Molecular Imprinting

New items RSS feed
new items RSS feed  View latest updates

Sign-up for e-mail updates:
Choose between receiving an occasional newsletter or more frequent e-mail alerts.
Click here to go to the sign-up page.


Is your name elemental or peptidic? Enter your name and find out by clicking either of the buttons below!
Other products you may like:
view listings for MIP books on eBay:



Mickey Mouse 90th Anniversary banner