Abstract: A rapid, sensitive and accurate method for the simultaneous determination of 5 kinds of chlorophenols (CPs) in seawater samples by dispersive magnetic solid phase extraction-liquid chromatography (dMSPE-HPLC) was developed. The seawater samples were firstly enriched with pentachlorophenol-imprinted amino-functionalized nano-Fe3O4-polymer magnetic composite material (nFe3O4@MIPNH2-polymer), then separated on a C8 analytic column (250 mm x 4.6 mm x 5.0 μm) using methanol-NH4Ac solution (70:30) as mobile phase and detected at 230 nm via UV detector. The results showed that under the optimal condition, the calibration curves were linear in the range of 1-5000 ng/L with correlation coefficients (r2) higher than 0.9989 for target chlorophenols. The spiked recoveries were between 86.5% and 98.8% with relative standard deviations (RSDs) of 0.8%-8.6%. The limits of detection (LODs) were in the range of 0.18-1.20 ng/L and the limits of quantitation (LOQs) were between 0.6 ng/L and 4.0 ng/L. The developed method could be applied in the routine analysis of chlorophenols in seawater samples.
Template and target information: pentachlorophenol, chlorophenols
Author keywords: amino-functionalized, molecular-imprinted magnetic material, Chlorophenols, seawater, dispersive solid phase extraction (dMSPE)