Abstract: A molecularly imprinted electrochemical sensor was prepared by radical thermal polymerization with gallic acid (GA) as a template molecule and methacrylic acid as a functional monomer. Cyclic voltammetry and square wave voltammetry were applied to the investigation of the analytical performance of the sensor. The results indicated that the method had high selectivity and reproducibility. The difference of peak current showed a linear dependence on the concentration of gallic acid in the range of 4.69 x 10-6 - 2.14 x 10-5 mol/L, with a detection limit of 6.41 x 10-7 mol/L. The MIPs sensor was applied to the detection of GA in the pill of liuweidihuang samples. The average recoveries ranged from 95.1% to 104.8%.
Template and target information: gallic acid
Author keywords: molecularly imprinted polymer, Electrochemical sensor, Gallic acid, voltammetry