Abstract: A magnetic molecularly imprinting polymer for domoic acid was fabricated. Synthesis conditions were optimized. The polymer particles have high magnetization for rapid magnetic separation. The apparent maximum absorption amount and dissociation constant of the polymer were 1,600 μg g-1 and 20.6 μg mL-1, respectively. The polymer retained 90% of adsorption amount after 5 times of repeated use. It was used as an adsorbent for purification and HPLC detection of domoic acid in shellfish with a detection limit of 0.050 μg g-1. Thus, the polymer could be applied to the sample pretreatment of aquatic products
Template and target information: 1,3,5-pentanetricarboxylic acid, PTA, dummy template, domoic acid
Author keywords: Domoic acid, liquid chromatography, magnetic molecularly imprinting polymer, Shellfish