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Reference type: Journal
Authors: Yao SZ, Peng H, Liang CD, Wu Y, Nie LH
Article Title: Biomimetic bulk acoustic wave sensor for determination of trimethoprim in the organic phase based on a molecular imprinting polymer.
Publication date: 2000
Journal: Analytical Sciences
Volume: 16
Issue: (2)
Page numbers: 211-215.
DOI: 10.2116/analsci.16.211
Alternative URL: http://www.jstage.jst.go.jp/article/analsci/16/2/211/_pdf

Abstract: A molecular imprinted polymer was prepared using trimethoprim as the template molecule and methacrylic acid as the functional monomer by a non-covalent method. The powders of the polymer were coated on one electrode of a bulk acoustic wave (BAW) device to construct a biomimetic sensor for the determination of trimethoprim. In absolute ethanol, the sensor exhibited good selectivity and sensitivity. In the range of 6.0x10(-8) - 6.7x10(-5) M, there was a linear relationship between log(-Delta f) and log C. The detection limit was 4.0x10(-8) M. When treated by heat, heavy metal salt, acid, etc., the sensor still exhibited long-time stability and resistance to such harsh chemical environments. Satisfactory results of a real sample assay were obtained by the proposed method
Template and target information: trimethoprim


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