MIPdatabase
Authors: Karfa P, Madhuri R, Sharma PK, Bhattacharya S, Singh S, Das A, Basu S
Article Title: Development of carbon dots modified fluorescent molecular imprinted Polymer@Ag/AgCl nanoparticle for hepatocellular carcinoma marker.
Publication date: 2017
Journal: AIP Conference Proceedings
Volume: 1832
Issue: (1)
Page numbers: ArticleNo050008.
DOI: 10.1063/1.4980241
Alternative URL: http://aip.scitation.org/doi/pdf/10.1063/1.4980241
Abstract: In this work, a sensitive and selective fluorescent molecularly imprinted polymer (MIP) was developed for detection of hepatocellular carcinoma (HCC) biomarker i.e. alpha feto protein (AFP) using Ag/AgCl as platform. Here, the carbon dots and Ag/AgCl nanoparticles were functionalized with vinyl groups and used as functional monomer for synthesis of AFP-imprinted polymer. The imprinted polymer shows a linear range of 3.96 ng mL-1 to 80.0 ng mL-1 with detection limit of 0.42 ng mL-1.The adsorption property of the MIP@Ag/AgCl was studied and shows the high affinity binding towards their target analyte without any cross-reactivity and false-positive or false-negative results
Template and target information: protein, alpha feto protein, AFP
Author keywords: fluorescent sensor, Ag, AgCl nanoparticle, molecular imprinted polymer, Alpha feto protein
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